COVID-19 Scan for Apr 08, 2022

COVID-19 test-to-stay methods secure, efficient for college kids

A examine as we speak in Pediatrics suggests a test-to-stay (TTS) technique, versus quarantine, was a secure and efficient software for Massachusetts public faculties for the 2021-22 college yr, because it was related to each restricted COVID-19 transmission and elevated in-person studying days for college kids.

The TTS program required all college students uncovered to a COVID-19 case within the classroom to make use of a fast antigen check for 7 days following the final publicity date. If the check was damaging, college students might stay in class. This system was opt-in, and for college kids who selected to not take part, an publicity resulted in at-home quarantine for not less than 7 days following any in-school shut contact if the coed was not absolutely vaccinated.

A complete of two,298 faculties signed up for TTS, and throughout the first 13 weeks of this system (September to December 2021) 1,959 faculties used TTS for 102,373 particular person, uncovered college students. Out of 328,271 assessments carried out, 2,943 optimistic circumstances have been recognized, for a per-person positivity fee of two.9%, just like throughout obligatory quarantine the yr earlier than.

The authors mentioned the TTS program resulted in a minimal of 325,328 and a most of 497,150 days of in-person college for members that might have been misplaced to quarantine.

Whereas the examine outcomes have been encouraging, a commentary in the identical journal argued that TTS might not work for under-resourced faculties and college students. The authors are John Neatherlin, MPH, and Lisa Barrios, DrPH, ScM, of the Facilities for Illness Management and Prevention, and Ebony Thomas, MPH, of Emory College.

“If TTS members should search testing locally, boundaries together with out-of-pocket prices, transportation logistics, and entry to well being care provider-based testing have to be addressed,” the commentators wrote.

“Unvaccinated college students in class districts with out the capability to implement TTS, and college students in TTS districts who’ve boundaries to decide in to those packages, might not have equal entry to in-person studying. Rising entry to and uptake of COVID-19 vaccines will permit extra college students to remain within the classroom.”
Apr 8 Pediatrics study and commentary


Omicron COVID-19 infections seem milder, shorter than Delta circumstances

An observational examine yesterday in The Lancet means that COVID-19 infections with the Omicron subvariant have much less involvement of the decrease respiratory tract, decrease odds of hospitalization, and shorter period of sickness and infectiousness than Delta circumstances.

Led by King’s Faculty London researchers, the potential examine recruited 63,002 UK residents aged 16 years and older reporting their COVID-19 check outcomes and signs in a smartphone app from Jun 1, 2021, to Jan 17, 2022. Individuals had examined optimistic for COVID-19, have been symptomatic, and had acquired not less than two doses of any COVID-19 vaccine.

The first examine final result was the chance of getting any of 32 signs monitored within the app or being hospitalized inside 7 days earlier than or after testing optimistic throughout the interval of Delta (Jun 1 to Nov 27, 2021) versus Omicron (Dec 20, 2021, to Jan 17, 2022) dominance.

Within the first interval, Delta was chargeable for greater than 70% of all circumstances in the UK and for COVID-19 infections amongst 4,990 members matched for age, intercourse, and vaccine dose with 4,990 contaminated throughout the interval by which Omicron was chargeable for greater than 70% of infections.

Individuals reported much less lack of odor throughout the Omicron interval than throughout Delta (16.7% vs 52.7%; odds ratio [OR], 0.17), however sore throat was extra frequent throughout Omicron than Delta (70.5% vs 60.8%; OR, 1.55). Hospitalization was much less frequent throughout Omicron than Delta (1.9% vs 2.6%; OR, 0.75).

“The prevalence of signs that characterise an omicron an infection differs from these of the delta SARS-CoV-2 variant,” the examine authors wrote. “Our knowledge point out a shorter interval of sickness and doubtlessly of infectiousness, which ought to influence work–well being insurance policies and public well being recommendation.”

In a associated commentary, Linda Houhamdi, PharmD, PhD, and Pierre-Edouard Fournier, MD, PhD, each of Aix-Marseille Universite in France, famous that folks youthful than 16 years and those that have been overweight have been excluded from the examine. “Certainly, omicron circumstances have been reported in sufferers youthful than 16 years, and weight problems is an indeniable comorbidity issue within the severity of COVID-19.”
Apr 7 Lancet study and commentary

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