News Scan for May 02, 2022

COVID vaccine uptake at Minnesota office rose after $1,000 incentive

The speed of full COVID-19 vaccination amongst staff of a personal Minnesota medical machine producer rose 10.4 share factors after the corporate started providing $1,000 incentives for immunization, finds a research printed late final week in JAMA Community Open.

Researchers from Starkey Listening to Applied sciences and the College of Minnesota studied COVID-19 vaccination outcomes at Starkey from the inducement interval of Aug 6 to Sep 30, 2021. Workers who agreed to look at and acknowledge an internet academic program and present proof of two doses of an mRNA vaccine acquired $1,000 in October.

Knowledge, together with the vaccine model and dates of every dose, have been entered right into a human sources database and mixed with info on worker age, wage band, intercourse, and race.

By Sep 30, 2,055 of two,099 (97.9%) employees eligible for the inducement reported their vaccination standing. Of the two,055 staff, 54.7% have been ladies, 75.5% have been White, 12.5% have been Asian, and 6.8% have been Hispanic.

Earlier than the inducement was supplied, 75.7% of staff have been totally vaccinated towards COVID-19, a determine that rose to 86.1% after, for a ten.4 percentage-point enhance. Of 500 staff who had acquired one or no vaccine doses earlier than, 42.8% have been totally vaccinated by research finish.

Within the weeks main as much as the inducement announcement, charges of staff receiving their first and second vaccine doses have been flat. However the week of the announcement, 54 extra staff (95% confidence interval [CI], 29 to 79) acquired their first vaccine dose, and 70 extra employees (95% CI, 30 to 110) acquired their second dose.

The next proportion of ladies than males have been vaccinated after the inducement was supplied (45.3% vs 38.2%). In contrast with their White and Black counterparts, Asian employees had increased ranges of vaccine uptake (52.4% vs 43.6% vs 15.4%). Vaccination charges did not differ considerably by age-group or wage vary.

“Limitations of the research embrace absence of a management group, being restricted to a single firm, and attainable confounding with full approval of the Pfizer vaccine by the FDA on August 23, 2021,” the research authors wrote.
Apr 29 JAMA Netw Open research letter


Flu vaccination related to 34% decrease danger of cardiac occasions

A brand new meta-analysis of six randomized managed trials finds that seasonal influenza vaccination was related to a 34% decrease danger of main hostile cardiovascular occasions, and other people with a latest acute coronary occasion had a forty five% decrease danger. The research additionally appeared in JAMA Community Open.

The research befell from 2000 to 2021 and included individuals who have been randomized to obtain both a flu vaccine or placebo. The research included 9,001 sufferers at a mean age of 65.5 years; 52.3% had a earlier cardiac occasion.

The authors discovered that 3.6% of vaccinated sufferers developed a significant hostile cardiovascular occasion inside 12 months of flu vaccination, in contrast with 5.4% of those that acquired placebo or management. This implies 56 folks must be vaccinated to forestall 1 cardiac occasion.

All informed, 1.7% of vaccine recipients died of cardiovascular causes, in contrast with 2.5% of placebo or management recipients, for a 26% decrease danger (danger discount, 0.74; 95% confidence interval, 0.42 to 1.30; P = .29).

“The impact sizes reported right here for main hostile cardiovascular occasions and cardiovascular mortality (in sufferers with and with out latest ACS [acute coronary syndrome]) are comparable with—if not higher than—these seen with guideline-recommended mainstays of cardiovascular remedy, resembling aspirin, angiotensin-converting enzyme inhibitors, β-blockers, statins, and twin antiplatelet remedy,” the authors concluded.
Apr 29 JAMA Netw Open


WHO particulars Australia’s latest Japanese encephalitis virus spike

Since March, when Australia declared a communicable illness incident of significance after a domestically acquired case of Japanese encephalitis virus (JEV), the nation has reported 35 circumstances—25 suspected and 12 possible—throughout 4 states, the World Well being Group (WHO) mentioned in an outbreak discover final week.

Three deaths have been reported, and the newest symptom onset was Mar 14.

The circumstances are the primary on Australia’s mainland since 1998. JEV is a mosquito-borne virus that primarily impacts pigs and horses, however infectious pigs can amplify circulation in mosquitoes, which may transmit the illness to people. The 4 affected states are New South Wales, Queensland, South Australia, and Victoria.

The circumstances this yr are unusually excessive, on condition that Australia had reported solely 15 JEV circumstances over the previous decade. Of these, just one was acquired in Australia.

As of Apr 20, JEV has been detected on 73 pig farms throughout the identical 4 states. Scientists are working to find out which mosquito species are most vital within the unfold of the illness in Australia. The WHO added that almost all circumstances are asymptomatic, however in these with scientific illness, the case-fatality fee could be as excessive as 30%, and a few neurologic penalties could be everlasting. There aren’t any therapies, and vaccination is normally solely suggested for folks in sure danger teams.

The onset of colder months in southern Australia might scale back mosquito populations and transmission, the WHO mentioned, including that the regional and world danger stage is at the moment low.
Apr 28 WHO outbreak notice
Mar 4 CIDRAP Information scan

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